Spontaneous Remission of Congenital Complete Atrioventricular Block in Anti-Ro/La Antibody-Negative Monozygotic Twins: Case Report
نویسندگان
چکیده
BACKGROUND Congenital complete atrioventricular block without any structural heart disease and anti-Ro/La negativity is very rare. Discordant complete atrioventricular block, which is more frequently defined in the literature as an autoimmune mechanism, is much more rare in monozygotic twins. CASE REPORT The 26-year-old healthy mother had given birth in her first spontaneous, uneventful pregnancy to monozygotic twins at week 35. While the first twin's physical examination proved her to be normal with a pulse rate consistent with her age, the second twin had a pulse rate of approximately 40 beats/minute.The patient was confirmed to have congenital complete atrioventricular block. CONCLUSION Despite this case appears to be an isolated one, a discordant complete atrioventricular block regression without any autoimmune evidence should be included in the differential diagnosis of bradycardia in infants.
منابع مشابه
Dizygotic twin with congenital AV block
The incidence of congenital atrioventricular (AV) block is estimated to be about 1 in 15,000-20,000 births. Although it is a rare disease, it increases fetal, neonatal, and childhood morbidity and mortality, and 60%-65% of all cases are reported to require pacemaker implantation before reaching adulthood (1). This disease can be idiopathic, but it is mostly caused by transmission of auto-antibo...
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